Proteomic Analysis Reveals Age-related Changes in Tendon Matrix Composition, with Age- and Injury-specific Matrix Fragmentation
نویسندگان
چکیده
منابع مشابه
Chavaunne T . Thorpe , John fragmentation age - and 1 injury - specific matrix withchanges in tendon matrix composition ,
Energy storing tendons, such as the human Achilles and equine superficial digital flexor tendon (SDFT), are highly prone to injury, the incidence of which increases with ageing. The cellular and molecular mechanisms that result in increased injury in aged tendons are not well established, but are thought to result in altered matrix turnover. However, little attempt has been made to fully charac...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2014
ISSN: 0021-9258
DOI: 10.1074/jbc.m114.566554